![]() Correction of distortions in optical coherence tomography imaging of the eye. Podoleanu, A., Charalambous, I., Plesea, L., Dogariu, A. Dynamic focus control in high-speed optical coherence tomography based on a microelectromechanical mirror. Three-dimensional and C-mode OCT imaging with a compact, frequency swept laser source at 1,300 nm. ![]() Dynamic focus in optical coherence tomography for retinal imaging. Interferometric synthetic aperture microscopy for extended focus optical coherence microscopy. Extended focus depth for Fourier domain optical coherence microscopy. High-resolution optical coherence tomography over a large depth range with an axicon lens. Focus-extension by depth-encoded synthetic aperture in optical coherence tomography. Ultrathin fiber probes with extended depth of focus for optical coherence tomography. Imaging the subcellular structure of human coronary atherosclerosis using micro–optical coherence tomography. Bessel beam spectral-domain high-resolution optical coherence tomography with micro-optic axicon providing extended focusing range. Extended focus high-speed swept source OCT with self-reconstructive illumination. Depth-of-focus extension in optical coherence tomography via multiple aperture synthesis. Interferometric synthetic aperture microscopy. in Optical Coherence Tomography: Technology and Applications (eds Drexler, W. Submicrometer axial resolution optical coherence tomography. With further optimization in optical designs to incorporate angular diversity into clinical instruments, OCRT could be widely applied as an enhancement over conventional OCT. We demonstrate greater than threefold improvement in lateral resolution as well as speckle reduction in imaging the tissue ultrastructure, consistent with histology. In correcting refraction-induced distortions to register the OCT images, OCRT also achieves spatially resolved refractive index imaging. Here, we introduce optical coherence refraction tomography (OCRT), which extends the superior axial resolution to the lateral dimension, synthesizing undistorted cross-sectional image reconstructions from multiple conventional images acquired with angular diversity. Furthermore, conventional OCT suffers from refraction-induced image distortions. Such anisotropic resolution can obscure fine ultrastructural features. Typical OCT systems sacrifice lateral resolution to achieve long depths of focus for bulk tissue imaging, and therefore tend to have better axial than lateral resolution. Published by John Wiley & Sons Ltd.Optical coherence tomography (OCT) is a cross-sectional, micrometre-scale imaging modality with widespread clinical application. © 2019 Acta Ophthalmologica Scandinavica Foundation. This study shows diurnal fluctuations of deep macular FD measured by OCTA and outlines the relationship between FD and hemodynamic parameters (MAP/HR) in POAG patients.īlood pressure diurnal variations flow density heart rate intraocular pressure open-angle glaucoma optical coherence tomography angiography. No statistically significant effect of IOP fluctuations on FD was observed. ![]() Superficial macular FD was influenced significantly by mean arterial pressure (MAP) (p = 0.006) and heart rate (HR) (p = 0.033), whereas FD in the RPC layer was significantly affected by HR (p = 0.010). While superficial macular FD and RPC FD revealed not to be affected by diurnal variations (p = 0.492, p = 0.319), FD in the deep layer of the macula increased throughout the day (p < 0.001). Diurnal variations in FD were analysed using linear mixed models. Intraocular pressure (IOP) and circulatory parameters were assessed accordingly. Optical coherence tomography angiography (OCTA) measurements were conducted at 08:00, 11:00, 15:00 and 20:00 over the course of two consecutive days. The retinal microvasculature of the macula (superficial and deep layers) and optic nerve was examined by OCTA (AngioVue ®, Optovue). To determine the diurnal variations in peripapillary and macular flow density (FD), as measured using optical coherence tomography angiography (OCTA) and to elaborate on the relationship between diurnal FD, circulatory parameters and intraocular pressure (IOP) variations in primary open-angle glaucoma (POAG).įorty eyes of 40 POAG patients were drawn into this cross-sectional study.
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